Taking up the challenges of His Holiness Pope Francis’ encyclical letter, Laudato sì, The Laudato sì Challenge mission is to put the principles of Laudato sì into responding to the cry of the poor and the cry of the earth through bold, coordinated and measurable action.. LSC strives to empower vulnerable people to “be the protagonist in their own solution,” supporting the vision of the Sustainable Development Goals of “being a human dignity narrative that leaves no one behind.” Laudato sì is our foundational stone, and our light of inspiration. To put the principles of this encyclical into action, The Laudato sì Challenge brings the precision and rigor of the venture philanthropy model together with the clarity, alignment and time-bound strengths of the “commitment model”—to drive focused, broad and sustainable impact (https://www.lsc21.org/commitments). LSC is a U.S. registered 501(c)(3) operating foundation whose donors and partners include: Rockefeller Capital Management, Acumen, Airbnb, Amazon Web Services, Blue Like an Orange Sustainable Capital, Biz Stone (Twitter co-founder), BNP Paribas, Conscious Ventures, Draper Associates, Noventi, SOCAP Global, TeraTree, The Embrey Family Foundation, and The University of Notre Dame.