Inspiral Biomedical Ltd has been established as a spin-out from the University of Manchester to maximise the use of our vast array of musculoskeletal samples, with associated medical data, in order to provide academic and industrial researchers access to this unique resource with the ultimate aim of improving patient care more quickly. In particular we have collected many thousands of biological samples, with linked data such as treatment response, therapy history, autoantibody status, CRP, HLA and whole genome genetic data, on samples collected at baseline before treatment and at 3 and 6 month follow-up, all of which are available for researchers to access.