Manufacturing processes can be unstable and reach high levels of scrap and rework. To achieve zero-defect manufacturing, Kapture.io, an Intelligent Quality Management System (QMS), integrates real-time control mechanisms, digital data collection for manual and automatic processes, AI algorithms focused on defect prediction, and Blockchain technologies to guarantee data traceability and validity. This set of solutions lead the way towards a real and cost-efficient “Quality 4.0.”