SINERGIA (Advanced technologieS for drug dIscovery and precisioN mEdicine: in vitRo modellinG human physiology and diseAse) is a project funded by the European Union in the framework of the H2020 Marie Skłodowska Curie Actions – Innovative Training Networks. SINERGIA aims to provide breakthrough strategies for the implementation of new in vitro preclinical platforms in terms of innovative technologies, biological models and drug screening approaches in the effort of bridging the gap between current, simplistic in vitro cultures and faithful and effective future physiological models.