The next revolution in biotechnology will be rationally designed ribonucleic acid (RNA)-based systems, molecular machines and devices. In order to prepare the next generation of RNA researchers, the University of Lethbridge, Université de Sherbrooke, and industry collaborators, have come together to offer the new RNA Innovation program. This unique partnership aims to produce highly qualified personnel with skills in advanced RNA research, scientific leadership, and industry experience. Trainees will develop professional skills in management, leadership, communication, and ethics. They will graduate with “job-ready” knowledge of applied and basic research and receive funding for on-site industry training and project development, while gaining access to leading industry partner collaborations. The RNA Innovation program is comprised of two key components, an entrepreneurial research and development challenge (deepYellow Challenge) and an extensive internship program (the Twinning Program). In the deepYellow Challenge, trainees will collaborate as a team to solve a complex scientific problem proposed by the program’s industry partners. Through the Twinning Program, all trainees will be matched with a specific industry internship, providing students with mentorship and a personalized networking experience. Contacts developed during this time will be extremely beneficial to the trainees for their future transition into the workforce. Competitive funding opportunities are available for MSc, PhD, and post-doctoral positions at this time. Interested applicants should have a minimum GPA of 3.5 in their last two years of undergraduate studies, although applicants with a lower GPA are still encouraged to apply if they have sufficient research and/or industry experience. Visit RNAInnovation.ca for information on how to apply.