The National Laboratory for High Performance Computing (NLHPC) is Chile's national supercomputing center. It specializes in high-performance computing and manages Guacolda-Leftraru, the most powerful supercomputer in the country and one of the most powerful in South America. Since its origin in 2011, it offers computing resources to the entire national scientific community in a centralized and equal manner. It fosters the collaboration of the country's scientific community around multi-, inter- and trans-disciplinary projects, to enhance the impact of this critical infrastructure on R&D&I, and ultimately on Chile's development. It also aims to contribute to national development beyond science, improving the competitiveness of the business fabric, and promoting innovation in the public sector.