The African Centre of Excellence for Genomics of Infectious Diseases (ACEGID), based at Redeemer’s University, Ede, Nigeria, is focused on driving innovation in viral genomics research, outbreak response, diagnostic development, and capacity building. Established in 2013 and supported by the World Bank and the US National Institutes of Health’s (NIH) H3Africa consortium, the ACEGID platform is building genomics pipelines, advancing our understanding of microbial threats, and training the next generation of African scientists how to identify, manage and control these threats. ACEGID is built upon strong collaborations forged across West Africa (Nigeria, Senegal, and Sierra Leone) and abroad (US, UK), allowing for increased reach and scalability of its innovations.