At the Ludeman Family Center for Women’s Health Research we perform cutting-edge research, mentor and fund the next generation of MD and PhD researchers, and educate the public and health care providers. In 2004, we became a center at the University of Colorado Anschutz Medical Campus because women’s health and sex differences have been significantly understudied. Greater knowledge about women’s health needs to be obtained so that both women and men are treated optimally. Because of the research gap, optimal preventions, treatments and cures for disease are lacking. We aim to accelerate a broadened research agenda in women’s health and sex differences, particularly in cardiovascular disease and diabetes. Cardiovascular disease and diabetes are leading causes of disability and death in women. These diseases are also often tied to struggles with depression and anxiety. We have seven senior scientists and over 60 affiliated junior MD and PhD, male and female scientists who study women’s health and sex differences across the lifespan from pregnancy and fetal programming, to children, adults, and the elderly. Our scientists include those who are experts in all types of science from the most basic to clinical/translational to epidemiologic to precision medicine. We have awarded over $1M through our peer review processes, while our young scientists have received over $60M in external funding. We have raised over $13M from private philanthropy and have a very involved Community Advisory Board. Our Scientific Council consists of prominent, internationally known scientists who are experts in the field of women’s health and sex difference research. We provide over 20 evidence-based educational programs each year to medical professionals, the scientific community and the public. We are working hard to speed progress and transform the future of women’s health. There is incredible opportunity before us – invaluable knowledge to be gained that will benefit everyone.