In 1961, the Daughters of Jesus started negotiations for a school site at BF Homes, Parañaque, south of Manila. This is in response to the call of the Church to open center of Catholic education outside Manila. Through the generous help of Don Jesus Cabarrus, the Hijas de Jesus were able to acquire a school site of 3 hectares. On June 19, 1971, Manresa School welcomed the first group of children into two-storey building. Sisters Angeles Garcia, F.I., Gertrudes Magdayao, F.I., Rosa Ortega, F.I. and Victoria Ruy, F.I. were the first Hijas de Jesus Sisters assigned to form a community to run the school. A year later, its door opened to the primary grades. Every year thereafter, a new grade level was added until the whole elementary department was completed. The school year 1977-1978 ushered in the high school department which opened to co-education. On March 26, 1981, the school witnessed its first fruits as sixty graduates received their high school diplomas. In the same year, the school was granted the permission to open the Nursery program which completed the Pre-School Department. In May 31, 2001, the school was granted the level 1 of PAASCU Accreditation. The Formal Survey took place in SY 2001-2002. On the same year, the High School Department started its PAASCU Preliminary Survey. In January 31, 2003, Manresa School was granted the level II PAASCU Accreditation for the High School Program. In S.Y. 2015-2016, Manresa School was granted the permit to offer a Senior High School program by the Department of Education. Science, Technology, Engineering and Mathematics (STEM) and General Academic Strand (GAS) were offered. In response to the present challenges of the new millennium, Manresa school continuously commits itself to the realization of its Vision-Mission through integral Catholic Education.