Sekolah Menengah Sains Muzaffar Syah (English: Muzaffar Syah Science Secondary School; abbreviated MOZAC) is the only science school and one of the two fully residential schools (Sekolah Berasrama Penuh) in the state of Malacca, Malaysia. Established in 1973 under the Second Malaysia Plan, it is the first boarding school in Malacca. The school is widely known as MOZAC and the students bears the name Muzaffarians. In 2010, the school was awarded with the Sekolah Berprestasi Tinggi or High Performance School, a title awarded to the 20 schools in Malaysia that have met stringent criteria including academic achievement, strength of alumni, international recognition, network and linkages. The school is specialised in green technology, agriculture, robotics and electronics. Most of the students became engineers and doctors.The school is a member of Strategic Educational Alliance of Southeast Asia.