We know that climate change is poised to reshape our world, but we lack clear enough predictions about precisely how. At CliMA, our mission is to provide the accurate and actionable scientific information needed to face the coming changes—to mitigate what is avoidable, and to adapt to what is not. We want to provide the predictions necessary to plan resilient infrastructure, adapt supply chains, devise efficient climate change mitigation policies, and assess the risks of climate-related hazards to vulnerable communities. We are a coalition of scientists, engineers, and applied mathematicians from Caltech, MIT, the Naval Postgraduate School, and NASA’s Jet Propulsion Laboratory. We are building a new Earth system model that leverages recent advances in the computational and data sciences to learn directly from a wealth of Earth observations from space and the ground. Our model will harness more data than ever before, providing a new level of accuracy to predictions of droughts, heat waves, and rainfall extremes. Our work is supported by a consortium of private foundations and federal agencies, led by the generosity of Eric and Wendy Schmidt by recommendation of the Schmidt Futures program, and including the Earthrise Alliance, National Science Foundation, and Paul G. Allen Family Foundation.