Formally established in 1998, the Centre for Health Evaluation and Outcome Sciences (CHÉOS) is an academic health sciences centre based at St. Paul’s Hospital in Vancouver, British Columbia, Canada. We are a collective of investigators who conduct high impact outcomes research. Our work is grounded in clinical need and informs health systems transformation in order to improve the health of populations. As a multidisciplinary research centre of the Providence Health Care Research Institute (PHCRI) and the University of British Columbia (UBC) Faculty of Medicine, CHÉOS is not disease, organ, or population specific. CHÉOS investigators evaluate the effectiveness of interventions across numerous health disciplines and aim to ensure that our work is relevant, addresses current gaps in delivery of care and contributes to overall system-wide improvements. In addition to conducting our own research, the inter-professional team at CHÉOS also provides practical expertise to other scientists. Our research support services include: methodological consultations, health economic services, clinical trial support, statistical analysis, and data management capabilities.