People who grapple with poverty, violence, trauma and oppression are often forced to make difficult tradeoffs that may provide short-term gains at the expense of their long-term wellbeing. Instead of interrupting these cycles, well-intentioned interventions may have the opposite effect, solidifying inequities that not only hold back individuals, but society as a whole. The Full Frame Initiative (FFI) partners with pioneering organizations, systems and communities across the country to fundamentally shift their focus from fixing problems to fostering wellbeing – the needs and experiences essential for health and hope. FFI demonstrates how this shift creates lasting change for people and opens the door for greater equity in society. Through a variety of tools – from policy, practice and culture change with partners; to thought-provoking insights that challenge the field; and mobilization of those who are ready for big change – FFI reveals how a new perspective can turn into new responses. We then amplify systemic successes to spur broader action and seed a movement for wellbeing. We will create possibilities for lasting change in people’s lives and spark a broader movement that replaces poverty, violence, trauma and oppression with wellbeing and justice.