AIMSS brings clinicians, epidemiologists and biomedical researchers together from Western Health, Victoria University and The University of Melbourne to bring researchers closer to the health system and to better influence healthcare delivery based on research. We aim to improve the health and wellbeing of the communities in which we live and work through innovative and integrative musculoskeletal research and advocacy. Our mission is to undertake focused, high quality, innovative research; foster collaborations with the research and general community; and promote healthy and active living in the communities we serve. AIMSS is leading the way in basic, translational and clinical research, and providing an environment that is cohesive, inclusive and inspiring to attract and retain a high-calibre workforce. We are continually developing interactions between clinicians, researchers and the community to promote healthy ageing and to improve the understanding, treatment and prevention of musculoskeletal disease. AIMSS has multiple ongoing collaborations with research institutes in Australia and around the world. Our strong network of collaborations allows us to have a major impact on musculoskeletal research worldwide.