Sustaining the high activity levels of maritime and coastal tourism and maritime transport and shipping sectors in Cyprus, require: (a) smart management of the country’s limited capabilities and resources via Maritime Spatial Planning, and (b) agile response measures for preserving the natural environment, securing society, and ensuring economic growth. MARI-Sense combines smart management and agile response capabilities into a family of cognitive systems equipped with perception, reasoning, learning, action, and intelligent resource allocation capabilities that enhance situational awareness under resource constraints imposed by the complex, wide-area, limited connectivity maritime environment. The primary general objective of the MARI-Sense project is the integration and adaptation of existing know-how and the development of novel knowledge and skills to develop the MARI-Sense Cognitive Decision Support System for Maritime Activities Planning, Emergency Response and Planning, and Maritime Spatial Planning. The secondary general objective is the contribution to smart, sustainable, and inclusive growth by establishing effective plans of growth powered by the diverse capabilities of members of the quadruple helix and general public that include a) Academic and Research institutions: University of Nicosia Research Foundation KIOS Research and Innovation Center of Excellence University of Cyprus, Computational Cognition Lab Open University of Cyprus, Cyprus University of Technology Laboratory for Underwater Systems and Technologies, University of Zagreb b) Enterprises: Cyprus Subsea Consulting and Services C.S.C.S. Ltd PHOEBE Research and Innovation Ltd T.C. Geomatic Ltd Algolysis Ltd Cyprus Research and Innovation Center Ltd AI ZEROCALIBER LTD c) Representatives of Industry and Public: Cyprus Employers’ and Industrialists’ Federation Limassol Nautical Club d) Government: Ministry of Defence