The Tilganga Institute of Ophthalmology (TIO) is the implementing body of the Nepal Eye Program (NEP), which was launched in 1992. TIO now consists of six divisions: (1) A full-service advanced clinical facility for eye care which delivers state-of-the-art services to patients. (2) An education training department which runs MD Residency Program in Ophthalmology, Certificate of Health Science (Ophthalmology) and short applied training for local & international medical personnel and eye health workers. (3) An outreach unit which runs rural district community eye centres and high-volume microsurgical eye clinics for the rural community throughout Nepal and committed similar efforts regularly in China, Bangladesh, Bhutan, India, Cambodia and North Korea. (4) An eye bank which undertakes cornea harvesting activity to provide corneas for corneal transplant operations and awareness programs for overcoming resistance to eye donation (5) A manufacturing facility which specialises in the production of world-class, state-of-the-art intraocular lenses (IOLs) for use in modern cataract surgery. The focus is always on affordability and uncompromised quality. (6) A research unit which focuses on improving clinical as well as operational activities. TIO has continuously involved itself in research activities for the development of eye care.