The Foundation’s mission is to support initiatives in evidence-based health care through training, mentorship, education, and collaboration. FURTHERING GRADE Reducing bias through methodological research and optimally applying the GRADE framework. SYSTEMATIC REVIEWS Developing structured literature reviews to identify, appraise, select and synthesize all research evidence relevant to a question. CLINICAL PRACTICE GUIDELINES Helping organizations succeed in providing actionable, evidence-based recommendations for individual patients and populations.