PRISMS, an acronym for Parents and Researchers Interested In Smith-Magenis Syndrome, is dedicated to providing information and support to families of persons with Smith-Magenis Syndrome (SMS), sponsoring research and fostering partnerships with professionals to increase awareness and understanding of SMS. Organized and incorporated in the state of Virginia on February 4, 1993, PRISMS, Inc. is governed by a volunteer Board of Directors. Most board members have children with Smith-Magenis Syndrome. PRISMS works closely with a multidisciplinary Professional Advisory Board that provides medical guidance and reviews research proposals. On May 4, 2000, the IRS declared PRISMS a 501c(3) non-profit organization. Our Federal Tax Identification Number is 54-1652029. We file an IRS form 990 every year. This form is available for public inspection at GuideStar.org or upon request.