Resulting from a double emergency, the lack of access to care for diabetic people in Africa and the lack of consideration of this issue by the development actors, the NGO Santé Diabète was founded to improve the prevention and management of diabetes in Africa. The NGO focuses its work on a comprehensive approach including all the axes for the establishment of prevention and quality care for diabetes : 1. Investing in primary prevention to reduce the human and economic burden of the disease progression 2. Investing in the decentralization of care to ensure geographic accessibility to a care of quality 3. Investing in secondary and tertiary prevention "therapeutic education" to reduce the burden of Diabetes complications 4. Investing in the reduction of care costs for geographic accessibility to a care of quality 5. Investing in an integrated approach including active involvement of patients and their families through their associations by promoting self-management mechanisms and advocacy 6. Investing in research - action to develop innovative approaches This approach is developed in the field with the institutional partners. This positioning into technical assistance to support prevention policies and treatment of diabetes implemented by the states ensures that the interventions done by the NGO can achieve long-term solutions. In parallel to these field operations, Santé diabète support many governments in the development or implementation of their policy against diabetes. More broadly, they also enable the NGO to develop expertise for many governments, international organizations, UN organizations. The results in the field have progressively make of the NGO Santé Diabète Mali a structure of reference for many international organizations (IDF, WHO..), scientific societies (French Society of Diabetes ...) and universities (University of Grenoble, University of Montreal, UCL London ...)