Initially funded by the European Commission’s Horizon 2020 programme, the first four ENABLE conferences were held in the cities hosting the headquarters of the four entities leading the project: the Institute for Research in Biomedicine (IRB Barcelona) in Barcelona, Spain; the Radboud Institute for Molecular Life Sciences (RIMLS) in Nijmegen, The Netherlands; The Novo Nordisk Foundation Center for Protein Research (CPR) in Copenhagen, Denmark; and the Scuola Europea di Medicina Molecolare (SEMM), in Milan, Italy. In this new cycle of conferences, FEBS, IUBMB and the four core ENABLE institutions have joined forces to share ENABLE best practices with other international research institutions. To this end, in addition to the four core research centres, other institutions can apply to become associated centres and host one of the events. For the 2024 event, FEBS-IUBMB-ENABLE will actively search for an associated centre in a non-European country to ensure that one of the events is held on another continent.