The Interdisciplinary Centre for Security, Reliability and Trust (SnT) is a research centre focused on Information and Communication Technology at the University of Luxembourg. In addition to long-term, high-risk research, SnT engages in demand driven collaborative projects with industry and the public sector creating socio-economic impact. Therefore the centre has set up a Partnership Programme with over 60 members targeting strategic areas addressing challenges confronting industry and the public sector in ICT. These resulting concepts present a genuine, long-lasting competitive advantage for companies in Luxembourg and beyond. SnT has undergone a rapid development since its launch in 2009; recruiting top scientists, launching over 50 EU and ESA projects, creating a technology transfer office (TTO), protecting and licensing IP, launching six spin-offs, and creating a dynamic interdisciplinary research environment with some 450+ people.