The Vanderbilt Ophthalmic Contract Research Organization (VO-CRO) is a research enterprise dedicated to producing highest quality pre-clinical data in a timely manner. VO-CRO provides a service platform that combines state-of-the-art technology with unparalleled expertise in ophthalmic disease modeling. This platform facilitates evaluation of the effectiveness of putative therapeutic strategies in clinically relevant models, and extends to assessment of both structure and function of ocular tissues. Our capabilities include, but are not limited to: in vitro screening for target identification/verification and mechanistic studies of drug mechanisms-of-action; in vivo rodent modeling of ocular pathologies; macroscopic and microscopic longitudinal morphological phenotyping; and longitudinal evaluation of retinal function and visual acuity.