The CPGR is a non-profit company located in Cape Town, South Africa, based on an initiative by the (DST), and financially supported by the Technology Innovation Agency (TIA). The CPGR combines state-of-the-art information-rich genomic and proteomic ('omics') technologies with bio-computational pipelines to render services and support projects in the life science and biomedical arena in (South) Africa, all run in an ISO 9001:2015 certified and ISO 17025 compliant quality management system. Among others, the CPGR has recently launched an accelerator program to stimulate the creation of South African start-ups based on 'omics' technologies and set up Artisan Biomed to develop and implement Precision Medicine solutions in (South) Africa. The organization uses the open-source Baobab LIMS for sample and data tracking; and, it has recently implemented a DRAGEN platform to enhance the development and execution of high-speed/high-volume NGS data-sets. CPGR also hosts DIPLOMICS, a large infrastructure program initiated by the DST. In December 2017, CPGR entered into a partnership with the Sunflower Fund to enhance stem cell donor typing in Africa. In support of Genomics capacity development in Africa, CPGR has launched an iScan system for high-end genotyping studies in early 2018. In April 2018, CPGR announced a new partnership to form a bespoke African biotech incubator, OneBio. Information about the CPGR can be obtained at www.cpgr.org.za and www.cpgr.org.za/blogspot.