As one of the largest private, multi-specialty medical groups in Missouri and Kansas, Signature Medical Group is a leader in quality and service. The organization was founded in 2001, when physicians joined to form the largest orthopedic physician group in St. Louis. Since then, Signature Medical Group has grown to include more than 135 highly respected physicians in various medical specialties. Signature Medical Group offers a full range of medical and surgical specialties including orthopedics, obstetrics, gynecology, family medicine, colon and rectal surgery, pediatrics, neurosurgery, allergy/immunology and surgical services.