Amsterdam Neuroscience is the research institute for neuroscience of Amsterdam UMC and the science faculties of Vrije Universiteit Amsterdam and the University of Amsterdam. Researchers and clinicians from these three institutions join forces in the field of fundamental, translational and clinical brain research. This collaboration strengthens the scientific excellence in this area, making Amsterdam Neuroscience one of the largest neuroscience communities in Europe. To enable translational neuroscience research, we develop and translate neuroscience knowledge into applications for patients. Amsterdam Neuroscience focuses on scientific excellence, young talent and innovation in four cross-disciplinary research programs. In addition, there are five clinical research programs that focus on both existing and new treatments for a number of brain and nervous system diseases, including neurological, neurovascular and psychiatric disorders. Amsterdam Neuroscience’s overall mission is to broaden the fundamental knowledge of the human brain and nervous system, and to translate this into effective therapies and treatments for the individual patient.