Real-time portable functional ultrasound neuro-imaging ICONEUS is introducing functional ultrasound neuro imaging: a breakthrough imaging modality for brain activity monitoring based on blood flow imaging with ultra-high sensitivity. For preclinical research, the portability and high versatility of our technology enables the study of brain activity at unprecedented scales and in a large variety of subject states: awake, behaving, freely-moving, resting-state and asleep conditions. Our technology can be easily combined with other complementary modalities such as eeg headstage or optogenetics which are inherently difficult to combine with fmri. Iconeus also offers key applications such as functional connectivity assessment between brain structures (connectomics) or stroke 4D monitoring. Building on years of preclinical expertise and research, we’re now investing and supporting exciting new clinical applications, using our Iconeus One CR functional ultrasound system dedicated to clinical research.