PhysioStim is recognized as one of Europe’s most reliable CROs specializing in cardiovascular safety pharmacology. Our experts offer electrophysiological studies and preclinical resources as well as their dedicated expertise in answering ICH S7A and S7B guidelines in accordance with GLP. We also respect the 3R principle and have already taken steps to comply with the upcoming CIPA guideline. PhysioStim has a history in excellence. Ever since our creation in 2000, PhysioStim has grown into a highly valued team that rises to the challenge of designing and conducting high quality studies for drug development. Our scientists are recognized for their expertise, reactivity, motivation and awarded with the loyalty of a consistently growing customer base. Overview of our services: - Human ion channel assays (manual or automated patch-clamp) - MEA+Impedance - Action potential recordings - Human cardiomyocytes isolated from iPS cells - ECG recordings and hemodynamic parameters (isolated Langendorff perfused heart) - Isolated organ baths (Contractility, Spontaneous beating frequency, vasoreactivity) - Compounds interaction - Telemetry