Our scientific mission is to integrate a theory of biophysics, including experience as sense, with other theories of nature. Our engineering mission is to develop technologies based upon successful theories. Our institutional goal is to establish a world~class international institute of scholarship, science and engineering focused on our missions. The scope of our scientific mission rests at the Foundations of Logic and Apprehension with the creation of theoretical models, the challenge of their rigorous and systematic formalization, and the verification of these models by observation in biophysics and practice. Pragmatically, the goal of our research is to explain the presence of experience in nature, and to do so with such fidelity that it becomes possible to provide a detailed account of the biophysical evolution and mechanics of sense and motility. This will enable us to also consider machines that experience. A product of our mission is a necessary new mechanics. This is a broad mandate with three natural levels of complementary research. Its scope spans the development of physical theory, the first principles of biophysical engineering, and the study of behavior in species. Success in these areas will provide contributions to the foundations of logic and mathematics, and inform the natural sciences and medicine.