Biology with X-ray Free Electron Lasers (BioXFEL) is a Science and Technology Center established by the National Science Foundation in 2013. Composed of eight U.S. research universities and aimed at addressing the fundamental questions in biology at the molecular level. Using a pulsed hard X-ray laser, our researchers can capture biological molecules in atomic detail, view their functional motions by taking brief snapshots, and observe interactions in their native environment. This opens up a new world to biology, to science, and to human health.