Established in 2006, Second City Outcomes Research LLC is a consulting company that specializes in pharmaceutical outcomes research. The company brings a depth and breadth of expertise ready to engage the many challenges and opportunities in today’s health care environment. Second City Outcomes Research LLC is led by four managing partners who are also established academicians. The partners have a wealth of experience and success leading outcomes research-based projects funded by both federal and non-federal government agencies as well as private sponsors including the pharmaceutical industry. The partnership has a history of collaborations with leading health outcomes researchers throughout the world that may be enlisted when unique methodological issues arise. This unique networking capability provides the company with tremendous depth. Particular areas of scientific expertise include large database analyses, pharmacoepidemiology, psychometrics, statistical modeling, decision analytic modeling, evaluation of patient-reported outcomes, methodological issues in economic evaluations of health care interventions, and applications such as budget impact models.