Latvian Institute of Organic Synthesis (LIOS) is a public research institute which possesses a broad spectrum of drug discovery and development process expertise including medicinal chemistry, organic synthesis, in vitro and in vivo pharmacology, bioanalytical studies, computational modelling, and process chemistry. LIOS has a long and positive experience in drug design and technology development, namely 18 original drugs were discovered and introduced into the market, more than 70 original reparation methods of known medicines were invented.