The Alliance for Regenerative Rehabilitation Research and Training (AR3T) is an NIH-funded resource center that is a collaboration between the University of Pittsburgh, Stanford University, Mayo Clinic, and the University of Texas Dell Medical School, with the goal of supporting the expansion of scientific knowledge, expertise and methodologies across the fields of regenerative medicine and rehabilitation, an intersection known as Regenerative Rehabilitation. AR3T is helping researchers around the country by providing education, training, research support, and funding opportunities. To accelerate scientific progress in this emerging field and to minimize disciplinary barriers, AR3T has assembled a multi-institutional network of laboratories that is conducting state-of-the-art research in stem cell biology, biomarkers, tissue plasticity and regeneration, biomaterials, bioengineering, cellular therapeutics, mechanotransduction, microtissue systems, animal models, gene therapy and imaging; and all are available to provide research support and opportunities to the research community through AR3T. Funding opportunities provided by AR3T support pilot projects and technology development, and are helping the field move forward.