The Unified Patient Network (UPN) is a community precision health ecosystem that accelerates the scientific advancement and clinical implementation of precision medicine via genomic sequencing and genetic counseling, research data assets and tools, and collaborative interoperability. A subsidiary of Seven Bridges Genomics, the UPN operates as a synergetic group of nonprofit academic health centers and other health systems participating in clinical research, enabled by the UPN through biopharma funding. The initiative aims to advance medical science and identify the genetic roots of human health and disease, by building a large database of research participants’ de-identified clinical and genomic data that will be available for research purposes – by researchers at UPN member health systems and biopharma companies.