GUNA was established over 25 years ago and is currently the leading Italian company in innovative medicine. GUNA is celebrated for its formulas, exemplary product quality and comprehensive medical and scientific research programs. What is different about GUNA A new generation of GUNA products is now in the USA: single cytokines. We are the only US pharmaceutical company offering single cytokines, the only available recombinant cytokines registered for systemic use.