It is well–recognized that the most effective healthcare systems arethose involving doctors, with specific training and education inmanagement, at the heart of management and strategic decision-making, in robust partnership with excellent managers. Doctors equipped with management skills have been shown to facilitatechanges and improvements, acting as facilitators and leaders. Evidence-based health care policy and management decisions within the systems,networks and pathways of patient care will be able to supportprofessionals in facing the rising and undefeatable challenges, influencingprocesses and guaranteeing quality improvement when patient safetyis at stake.