EBTC was founded in 2011 at the Johns Hopkins Bloomberg School of Public Health. EBTC's vision is to improve the public health outcomes and reduce human impact on the environment by bringing evidence-based approaches to safety sciences. We believe that adopting principles of transparency, objectivity and consistency, similar to Cochrane principles in clinical research, will allow regulators, industry and other stakeholders make more informed decisions about the effects of chemicals on human health and environment, determine the validity and accuracy of old and new tests, and eventually bring regulatory science in all industries and on all continents up to date with scientific advances. EBTC is planning to accomplish this by bringing all interested stakeholders together under EBTC’s roof to work on methodological challenges and to apply the evidence-based approaches to high-impact problems that involve safety decisions and serious public health implications.