KHPT is a not for profit entity that spearheads focused initiatives to improve the health and wellbeing of communities in India. In 2003, KHPT was founded with a single mission to reduce the prevalence of HIV in Karnataka’s high priority pockets. The initiative’s success made it a scalable model at national and global levels and KHPT became a learning site for innovative approaches. The unique DNA of our programs is a combination of evidence generation, grassroots community connect and government relationship. With these strengths, we learned and reflected on our decade long experience leading us to look beyond HIV to four other thematic areas. KHPT currently works on TB, HIV-AIDS, MNCH, adolescent health and comprehensive primary health care. Our bold social ambition to achieve population-level health impact through a systems change approach. With a team of 400+ individuals, we act as a catalyst driving action to empower and promote the health of the most vulnerable communities, both directly and through strong partnerships across the country. We work tirelessly to ensure that India achieves the SDG goal 3, good health and wellbeing of communities.