PIRE is an independent, nonprofit organization merging scientific knowledge and proven practice to create solutions that improve the health, safety and well-being of individuals, communities, and nations around the world. PIRE has a significant national presence in the area of applied science, with funded research projects at its centers on prevention, treatment, and policy research. PIRE scientists and practitioners continually focus on the design and implementation of complex program evaluation strategies and the conduct of research related to health and social issues, and criminal justice. PIRE practitioners and scientists provide training and technical assistance in many health-related areas to states and communities that are attempting to improve public health.