Hormone Therapy and Optimal Aging 25 Again is a recognized leader in Kentucky, Indiana, and Ohio for disease prevention and age management. If you're over 35, you are likely beginning to experience signs of aging through weight gain, energy loss, and maybe even depression. By age 40, many have lost over 50% of their prime hormone levels. Through hormone therapy and optimization, we are successful at putting you on the path to feeling as good as you've ever felt in your life, while simultaneously fighting disease. Our courses of treatment are specifically designed to change the way you think about taking care of yourself, inside and out. Thousands of men and women from all over Kentucky and Southern Indiana have increased energy, lost weight, and simply look and feel younger. The medical treatments are advanced, but the philosophy is simple. 25 Again gives you back what you once had.