Ataxia-Telangiectasia (A-T) is a progressive genetic condition which causes severe disability and shortens lives. The A-T Society exists to ensure that every life with A-T is lived to the full and to fund and promote research to develop treatments for the condition. We also support those living with closely-related conditions. Since 1989, the A-T Society has been leading the way in supporting people living with A-T and promoting research. We are in touch with almost every person known to have a diagnosis of AT in the UK and Ireland. In 1994 we established the first ever specialist A-T clinic in Nottingham and still work closely with the two specialist centres in the UK. We recently published the first -ever clinical guidance document, now available in English and French. In 2011, the A-T Society established the international A-T Clinical Research Network and a year later inaugurated (and continues to administer) a series of international clinical research conferences. Over the last 30 years we have funded a wide range of research projects and posts. We are currently leading work to establish an international A-T patient registry and are supporting the organisation of the first ever multi-centre clinical trial of a treatment for A-T, led by the Italian firm Erydel.