Center for Evolutionary Hologenomics study how interaction between genes and microbes determine biological evolution. The Center is directed by Professor Tom Gilbert and is part of the GLOBE Institute. The Danish National Research Foundation has funded the establishment of this new basic research center at the Faculty of Health and Medical Sciences, University of Copenhagen. Center for Evolutionary Hologenomics will develop and implement state of the art 'omics and associated computational techniques, and address through experimental and theoretical research, four fundamental questions about life on earth: - WHAT is the relationship between a host’s genome and the functional and taxonomic makeup of its associated microbial metagenome? - DOES this relationship explain ongoing ecological and evolutionary processes in the host? - COULD this relationship provide an alternate explanation to some of life’s big transitions? - HOW have we humans exploited this relationship?