Established in 1981, the Macao Polytechnic University (MPolyU) is a public multidisciplinary and application-oriented higher education institution (HEI) located in Macao, featuring academic excellence with an emphasis on both quality higher education and significant applied research that contributes to the sustainable development of society. MPolyU is the first HEI in Asia having a successful institutional review by the Quality Assurance Agency for Higher Education from the UK; the sole higher education institution in China receiving the Asia-Pacific Quality Awards from the Asia Pacific Quality Network; the first and only higher education institution in Macao winning the National Teaching Achievement Award; and the first higher education institution in Hong Kong and Macao housing a Ministry of Education Engineering Research Centre in machine translation and artificial intelligence. MPolyU excels in interdisciplinary research and innovation as a means to make its contributions to the sustainable development of humanities and societies. Such research studies focus on AI, machine translation, Portuguese language education, environment protection and intangible cultural heritage, which are powered through an array of research centres and laboratories. Its Chinese-Portuguese Neural Network Machine Translation Platform achieves the highest translation accuracy worldwide. MPolyU boasts a robust network of partnerships fostering academic exchange, outcome-based teaching, research collaboration, dual degree and joint programmes with prestigious institutions, corporations and organisations worldwide. The Research Centre in Ubiquitous Computing in partnership with the Henry Samueli School of Engineering and Applied Science of the UCLA, is an example of these collaborative ventures at MPolyU. Setting off from MPolyU students, alumni and staff are realising their prowess in different walks of life, creating opportunities for the betterment of the local community and afar.