HRB NCTO, is an integrated Clinical Trial network, aligned to the local supports of the existing clinical trials infrastructures to ensure a harmonised strategic national approach to the conduct of high-quality clinical trials in Ireland. The HRB NCTO central office provides overarching support and expertise, through a range of services and activities to academia and industry. The partner CRF/Cs provide the infrastructure, physical space and facilities, experienced research and specialist support staff and the necessary quality and oversight programs that are critical for the successful conduct of world-class patient-focused research.