AICROS, the Association of International CROs, is an official operative network of small to midsize CROs which provide clinical research services for the medical device, pharmaceutical and biotech industry for many years. Through our experience we fully understand the needs of Sponsors, we always find time to listen their requirements, their wishes and their typical complaints about the CRO business. We have learned that low quality providers - slow but expensive global CROs - are missing client orientation, high staff turnover or just lack of CRO staff competence therefore they caused frustration in the past experience of our clients. Everybody considers small to midsize CROs as much better service providers, however Sponsors are less confident that they can handle multinational trials. Based on this knowledge we decided to follow a different approach which combines the advantages of large and small to midsize CROs and offering the reliability of a global CRO.