The Croatian Institute for Brain Research (CIBR) is the most prominent institution in the field of neuroscience in the Republic of Croatia. The CIBR is an important research and teaching institution at the School of Medicine, University of Zagreb, and is also affiliated with the University Clinical Hospital Center Zagreb (CHC Zagreb). At present, the CIBR co-ordinates the largest biomedical research programme (encompassing 30 individual research grants) in Croatia. The CIBR is dedicated to promoting research and education in basic and clinical neuroscience, and has been instrumental in developing translational approaches in neuroscience, which resulted in several major translation programmes, namely: molecular basis of neurodegenerative processes in cognitive disorders; developmental cognitive and mental disorders; and neuroimaging of the central nervous system. In addition, the CIBR has been focused on integration of existing research facilities in joint translational research programmes at the School of Medicine, University of Zagreb.