VU-ISIS conducts basic and applied research in the area of systems and information science and engineering. Applications of ISIS technology span a wide range of software-intensive systems from small embedded devices, through real-time distributed systems, to globally deployed complex systems. Software is increasingly essential to the functions of these systems, and it is also the primary means of adapting them to their environments and users. Our research interests lie in the theoretical foundations, modeling, design, engineering, and educational aspects of these systems.