Our team of physiologists and pharmacologists offers a unique platform with a wide range of in vitro and in vivo assays : - In vitro Safety & Efficacy Evaluation: We have developed an innovative amperometry-based method for the ultrasensitive detection Reactive Oxygen Species (NO and H2O2) in real time, which can be used to predict the antioxidant capacity of new skin treatment compounds. - Intestinal contraction: The gut motility describes the inherent ability of the smooth muscle constituting the wall of the intestine to contract spontaneously and rhythmically. This phenomenon is mostly dependent of enteric nervous system, particularly the myenteric plexus. This assessment allows: - Screening of potential compounds - Identification of the targeted intestinal segments (duodenum, jejunum, ileum and colon) - Characterization or consolidation of the therapeutic effects - Characterization or consolidation of the mechanism of action involving the enteric nervous system - Repositioning of your compound ENTEROSYS adresses different markets Dermocosmetic: - Validation of the antioxidant activity of your compounds on skin models, either short or long-term: (NMEs, natural extracts, formulations, etc.), - Comparison of the the antioxidant profile of your bioactive molecules to a reference compound - Using our proprietary skin models, adapt them or develop tailor-made models Nutraceutic: - Screening of potential compounds - Improved lead profiling and selection - Characterization or consolidation of the therapeutic effects - Characterization or consolidation the mechanism of action - Repositioning of your compound Biotech and pharma: - Screening of potential compounds - Improving lead profiling and selection - Characterization or consolidation of the therapeutic effects - Characterization or consolidation the mechanism of action - Repositioning of your compound