CVCT meetings are oriented toward brainstorming and intense interaction, among leaders from various backgrounds assembling in a unique think tank. Rather than simple lecturing, and beyond the educational aims, sessions provide ample time for panel discussion among the think tank members and with delegates. Pharmaceutical and health industry should view this initiative differently from a simple promotional/educational meeting. Supporting/attending CVCT will contribute to better understanding local health care systems and governmental policies, disease burden, clinical practice patterns and unmet needs as well as ways for the optimal implementation of major recent therapeutic innovations. The fist CVCT ME forum was held successfully in Abu Dhabi in 14th – 16th of April 2016 With representatives from France, Germany, Switzerland, USA, Saudia Arabia, Bahrain, United Arab Emirates, Tunisia, Egypt, Lebanon, Oman, Jordan, Turkey and Iran, it has assembled an eminent faculty with different background, including clinicians, epidemiologists, clinical trialists, policy makers, industry, regulatory, and international organisations, such as WHO. For the second edition, CVCT Forum ME is to expand to Mediterranean, African and Far East regions and will be held in Cairo. It aims to involve the WHO regions of EMRO (East Mediterranean Region Organisation) from West (Morocco) to East (Pakistan) and from North (Algeria) to south (South Africa). Health care systems in these regions are diverse but they share more common economic, epidemiological and environmental features than with other regions in the world.