PKDERM offers innovative and intelligent solutions for the in vitro evaluation of safety and efficacy. The company is located in Grasse, in the south of France and aims to support partners in the area of cosmetics, dermatology, pharmaceutical, chemical, agro/petrochamical, and medical device industries. At PKDERM, we are familiar with an array of different assay systems to evaluate the safety and efficacy of new products. This allows us to work with our clients to determine the optimum assay that best fit their needs. Our acknowledged experience with our worldwide network of multidisciplinary partners enable us to rapidly support our customers confronted with new urgent testing needs. Our biological models include but not limited to: 2D culture of human skin cells (keratinocytes, fibroblasts, melanocytes), 3D human skin equivalent models, excised human skin, 2D and 3D human hepatocytes, 2D and 3D human lung models. Our in vitro safety testing includes but not limited to: dermal absorption, skin irritation, eye irritation, skin sensitization, cytotoxicity, phototoxicity, endocrine properties, metabolism, drug transporters and drug-drug interactions. Our in vitro efficacy testing includes but not limited to: dermal and nail absorption, anti-inflammatory properties, pigmentation, ageing, wound healing, ... We provide personalized service for every client and every project and we support the development of new products from the initial reflection and conceptualization to the data promotion and publication. We perform standard testing services as well as optimizing and validating new alternative assays. On the other hand, PKDERM offers scientific and project management services related to alternative methods to animal testing and provides workshops and practical training on the use of in vitro methods. Please do not hesitate to contact us if you need further assistance, have questions or need to place an order.