Contract Fermentation and Bioprocessing CBB offers an experienced professional staff and state-of-the-art fermentation and purification facilities to perform confidential contract services. Operations are smoothly transferred from the main facility to GMP. In 2004, CBB acquired the current Good Manufacturing Practices (cGMP) facility with three protein purification suites. In 2007, CBB completed a cGMP fermentation suite containing 30, 100 and 300-liter fermentors. The GMP facilities are located on the University of Iowa Research Park adjacent to the CBB's Research and Process Development Laboratory. The CBB develops, evaluates, optimizes, and scales up bio-based products in volumes ranging from 1 to 1,000-L. Typically, they bring research findings from the bench through the first stages of scale-up. The more than 20-member lab staff's extensive experience includes a wide-range of organisms, notably high-cell-density recombinant E.coli and Pichia pastoris. Products produced cover the complete range of interest - vaccines, enzymes, immobilized catalysts, antibiotics, therapeutics, nucleotides, polysaccharides, peptides, polymers, and biochemicals. The development process is rapid, economical and can be easily transferred to CBB cGMP Laboratory. CBB produces bulk biopharmaceuticals for evaluation. The Center has considerable experience purifying fermentation-produced biological materials. Biotech. Research and Education Education and research are major interests of the CBB. Currently, the predoctoral program supports six fellows. These fellowships provide interdisciplinary research training that focuses on the applications of engineering, physics, chemistry, mathematics, biochemistry, and biology to those areas of research related to biotechnology. Faculties from the physical, engineering, and biological sciences support a curriculum that bridges these disciplines, essential for biotechnology training programs.